Project Description: Intestinal parasites and malaria remain a major public health issue is Sub-Saharan Africa and, more often than not, overlap. Malaria remains an important cause of morbidity and morality, particulary in Africa where 90% of the cases occur. In Sub-Saharan Africa alone, morality and morbility due to malarai accounts for a loss of 35.4 million DALYS. From 1982 to1984 a longitudinal study on the health status of children was undertaken in Kikwawila village, a typical settlement... Intestinal parasites and malaria remain a major public health issue is Sub-Saharan Africa and, more often than not, overlap. Malaria remains an important cause of morbidity and morality, particulary in Africa where 90% of the cases occur. In Sub-Saharan Africa alone, morality and morbility due to malarai accounts for a loss of 35.4 million DALYS. From 1982 to1984 a longitudinal study on the health status of children was undertaken in Kikwawila village, a typical settlement of the kilombero valley in south-eastern Tanzania which nowadays belongs to the Kibaoni ward. This longitudinal study found that malaria was hol- to hyperendemic in the community, P. falciparum being responsible for more than 90% of the infections. Transmission of malaria was high and stable as indicated by a parasite rate of 80% among infants between 1 month and 1 year. Giardia lamblia, hookworm (Nectoramericanus), Strongyloides spp. and S. haematobium were highly prevalent, while Entamoeba histolytica, Ascaris lumbricoides and Trichuris trichiura were of minor importance. The anthropometric assessment showed a high prevalence of stunting (35%-71%) and a substantial prevalence of wasting (3-20%). Nutrients effects were difficult to unravel. We are aiming to conduct an in-depth examination of the parasitic infections in 500 children in kibaoni ward including parasitological, anthropometric, and clinical parameters. Additionally, anamnestic analysis will be performed from a full blood sample.
Principal Investigator : Emmanuel Mrimi
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Time frame: (2019-01-01) - (2019-06-30)